• Cochlioquinone A, EvoPure� packaged and labeled in glass vial.

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SKU: C179

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Description
Cochlioquinone A is the major component of a bioactive pigment isolated from Bipolaris leersia. Cochlioquinone A is anti-angiogenic and exhibits inhibitory activity against diacylglycerol acyltransferase and NADH-ubiquinone reductase.

Cochlioquinone A is soluble in ethanol, methanol, DMF and DMSO.

    CAS Number

    32450-25-2

    Molecular Formula

    C30H44O8

    Molecular Weight

    532.7

    Mechanism of Action

    Cochlioquinone A is an antagonist of the human chemokine receptor, CCR5, in HIV-1.

    Storage Conditions

    -20°C

Specifications

    Appearance

    Yellow Lyophilisate

References

    References

    Cochlioquinones and epi-cochlioquinones: antagonists of the human chemokine receptor CCR5 from Bipolaris brizae and Stachybotrys chartarum. Yoganathan K., et al. , J. Antibiot. 2004, 57, 59. 

    Cochlioquinone A1, a new anti-angiogenic agent from Bipolaris zeicola. Jung H.J. et al. , Bioorg. Med. Chem. 2003, 11, 4743. 

    Inhibitory activity of diacylglycerol acyltransferase by cochlioquinones A and A1. Lee H.B. et al. , J. Antibiot. 2003, 56, 967. 

    Phytotoxic compounds cochlioquinones are inhibitors of mitochondrial NADH-ubiquinone reductase. Lim C.-H. et al. , J. Pesticide Sci. 1996, 21, 213.

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