• Clotrimazole packaged and labeled.

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SKU: C037

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Description

Clotrimazole is a freely soluble (30 mg/mL) antifungal which targets the cell membrane.

    CAS Number

    23593-75-1

    Molecular Formula

    C22H17ClN2

    Molecular Weight

    344.84

    Mechanism of Action

    Clotrimazole increases fungal cell permeability by inhibiting ergosterol synthesis, a major cell membrane component found exclusively in fungi.

    Storage Conditions

    2-8°C

    Tariff Code

    2933.29.2000

    Spectrum

    Clotrimazole targets a broad range of fungi including Candida and Aspergillus species.

Specifications

    Form

    Powder

    Appearance

    White crystalline powder

    Source

    Synthetic

    Melting Point

    141- 145°C

    Assay

    (On Dried Basis): 98.5-100.5%

    Loss on Drying

    ≤0.5%

    Residue On Ignition

    ≤0.1%

    Heavy Metals

    Not more than 10ppm

    Impurities

    Clotrimazole A: ≤0.5%

References

    References

    Rice, Louis B., and Mahmoud A. Ghannoum. "Antifungal Agents: Mode of Action, Mechanisms of Resistance, and Correlation of These Mechanisms with Bacterial Resistance." Clinical Microbiology Reviews (1999): 501-17. www.ncbi.gov. Oct. 1999. Web. 22 Aug. 2012.

    "Clotrimazole." Dailymed.nih.gov. Glenmark Generics Inc., n.d. Web. 22 Aug. 2012

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