• Cisplatin

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SKU: C203

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Description
Cisplatin (cis-diammineplatinum(II) dichloride is a potent anti-tumor agent and is active against several types of solid tumors.

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    CAS Number

    15663-27-1

    Molecular Formula

    Cl2H6N2Pt

    Molecular Weight

    300.01

    Mechanism of Action

    Cisplatin interacts with DNA and forms intrastrand crosslink adducts which activate anti-tumor proteins ATR, p73, p53, and MAPK.

    Storage Conditions

    <30°C

References

    References

    Siddik, Zahid H. "Cisplatin: Mode of Cytotoxic Action and Molecular Basis of Resistance." Oncogene 22.47 (2003): 7265-279.

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