• Caspofungin acetate packaged and labeled.

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SKU: C103

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Description

Caspofungin acetate is a sparingly soluble (0.367 mg/mL) lipopeptide antifungal which specifically targets the fungal cell membrane.

    CAS Number

    179463-17-3

    Molecular Formula

    C52H88N10O15 • 2C2H4O2

    Molecular Weight

    1213.42

    Mechanism of Action

    Caspofungin acts as an inhibitor to β(1,3)-D-Glucan synthase, an enzyme which synthesizes β(1,3)-D-Glucan, a polysaccharide of D-glucose monomers found in the fungal cell wall.

    Storage Conditions

    -20°C

    Tariff Code

    2941.90.3000

    Spectrum

    Caspofungin acetate is used primarily against Aspergillus and Candida fungal species.

Specifications

    Form

    Powder

    Appearance

    White to off-White powder

    Source

    Semi-synthetic

    Water Content (Karl Fisher)

    ≤10.0%

    pH

    5.9-6..7

    Assay

    (As Is): 94.5-102.5%

    Sulfated Ash

    ≤0.5%

    Heavy Metals

    ≤20 ppm

References

    References

    Rice, Louis B., and Mahmoud A. Ghannoum. "Antifungal Agents: Mode of Action, Mechanisms of Resistance, and Correlation of These Mechanisms with Bacterial Resistance." Clinical Microbiology Reviews (1999): 501-17. www.ncbi.gov. Oct. 1999. Web. 22 Aug. 2012.

    "Caspofungin: Medical Use and Clinical Data." Drug Lib. Web. 22 Aug. 2012.

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