• Capreomycin packaged and labeled in glass vial.

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SKU: C162

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Description
Capreomycin is a complex of cyclic pentopeptides isolated from Streptomyces capreolus, first reported in 1962. The complex has two major components, IA and IB, with an exocyclic lysine residue and two minor delysinyl components, IIA and IIB. Capreomycin is a potent antibiotic with activity against mycobateria, Gram positive and Gram negative organisms.

Capreomycin is soluble in ethanol, methanol, DMF and DMSO.

    CAS Number

    11003-38-6

    Molecular Formula

    C25H44N14O7 (for IB)

    Molecular Weight

    652.7 (for IB)

    Mechanism of Action

    Capreomycin acts by binding to the 23S ribosomal subunit, disrupting protein synthesis.

    Storage Conditions

    -20┬░C

Specifications

    Appearance

    White solid

References

    References

    Chemical and biological properties of capreomycin and other peptide antibiotics. Herr E.B. Antimicrob. Agents Chemother. 1962, 1963, 201.

    Molecular basis for the selectivity of antituberculosis compounds capreomycin and viomycin. Akbergenov R. et al. Antimicrob. Agents Chemother. 2011, 55, 4712.

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