• Caffeic acid phenethyl ester (CAPE)

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SKU: C155

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Description
Caffeic acid phenethyl ester is a natural phenolic compound from honeybee hives and has demonstrated anti-carcinogenic, anti-bacterial, and antiinflammatory properties.

    CAS Number

    104594-70-9

    Molecular Formula

    C17H16O4

    Molecular Weight

    284.31

    Mechanism of Action

    Caffeic acid phenethyl ester inhibits bacterial growth by the production of reactive oxygen species (ROS) which disrupt the cell's outer membrane. Anti-inflammatory effects of CAPE arise from inhibiting the release of arachidonic acid from the cell membrane as well as inhibition of COX-1 and COX-2 activity.

    Storage Conditions

    -20°C

    Spectrum

    Caffeic acid phenethyl ester is active against Enterococcus faecalis, Listeria monocytogenes, Staphylococcus aureus, and Haemophilus influenzae.

Specifications

    Appearance

    Off-white crystalline powder

    Impurity Profile

    Individual Impurity: Not more than 0.3%

    Water Content (Karl Fisher)

    Not more than 0.2%

    Melting Point

    120 - 135°C

    Loss on Drying

    Not more than 0.2%

    Residue On Ignition

    Not more than 0.1%

    Heavy Metals

    Not more than 10ppm

References

    References

    Murtaza, Ghulam, Sabiha Karim, Muhammad Rouf Akram, Shujaat Ali Khan, Saira Azhar, Amara Mumtaz, and Muhammad Hassham Hassan Bin Asad. "Caffeic Acid Phenethyl Ester and Therapeutic Potentials." BioMed Research International 2014 (2014): 1-9. Web.

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