• Bicyclomycin packaged and labeled in glass vial.

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SKU: B048

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Description
Bicyclomycin is a polar metabolite first isolated from Streptomyces sapporonensis in 1972. The selective Gram negative profile of bicyclomycin is rare among Streptomyces metabolites.

Bicyclomycin is soluble in ethanol, methanol, DMF and DMSO. 

    CAS Number

    38129-37-2

    Molecular Formula

    C12H18N2O7

    Molecular Weight

    302.3

    Mechanism of Action

    The primary site of action for bicyclomycin is thought to be the rho transcription termination factor.

    Storage Conditions

    -20°C

Specifications

    Appearance

    White solid

References

    References

    Bicyclomycin, a new antibiotic I. Taxonomy, isolation and characterization. Miyoshi T. et al. J. Antibiot. 1972, 25, 569.

    Bicyclomycin, a new antibiotic II. Structural elucidation and acyl derivatives. Kamiya T. et al. J. Antibiot. 1972, 25, 576.

    Transcription termination factor rho: The site of bicyclomycin inhibition in Escherichia. Zwiefka A. et al. Biochemistry 1993, 32, 3564.

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