• Bestatin packaged and labeled in glass vial.

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SKU: B040

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Description
Bestatin is 'pseudo'-dipeptide isolated from Streptomyces olivreticuli in 1976. Bestatin is a potent aminopeptidase B inhibitor with no carboxypeptidase activity. Bestatin also exhibits antitumor activity and has been investigated in clinical trials.

Bestatin is soluble in ethanol, methanol, DMF and DMSO and is moderately soluble in water. 

    CAS Number

    58970-76-6

    Molecular Formula

    C16H24N2O4

    Molecular Weight

    308.4

    Mechanism of Action

    Bestatin acts as an immunomodulator by activating macrophages and T lymphocytes.

    Storage Conditions

    -20°C

Specifications

    Appearance

    White solid

References

    References

    Bestatin, an inhibitor of aminopeptidase B, produced by actinomycetes. Umezawa H. et al. J. Antibio. 1976, 29, 97. 

    The structure of bestatin. Suda H.. et al. J. Antibio. 1976, 29, 100. 

    Low-molecular-weight enzyme inhibitors of microbial origin. Umezawa H. Ann. Rev. Microbiol. 1982, 36, 75.

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