• Bafilomycin C1, EvoPure� packaged and labeled in glass vial.

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SKU: B042

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Description
Bafilomycin C1 is a member of a potent family of macrocyclic lactones. Bafilomycin C1 is broadly active against bacteria, fungi, insects, nematodes and cestodes. Bafilomycin C1 has attracted interest as a potential agent for treating osteoporosis. The presence of the fumarate group provides an ideal ligand for affinity chromatography of V-ATPase.

Bafilomycin C1 is soluble ethanol, methanol, DMF and DMSO. 

    CAS Number

    88979-61-7

    Molecular Formula

    C39H60O12

    Molecular Weight

    734.9

    Mechanism of Action

    Bafilomycin C1 is an inhibitor of vacuolar-type ATPase.

    Storage Conditions

    -20°C

Specifications

    Appearance

    White powder

References

    References

    Bafilolides, Potent Inhibitors of the Motility and Development of the Free-Living Stages of Parasitic Nematodes. Lacey E. et al. Int. J. Parasitol. 1995, 25, 349. 

    Purification of Vacuolar ATPase with Bafilomycin C1 Affinity Chromatography. Rautiala T.J. et al. Biochem. Biophys. Res. Comm. 1993, 194, 50. 

    Structure and function of V-ATPases in osteoclasts: potential therapeutic targets for the treatment of osteolysis. Xu J. et al. Histol. Histopathol. 2007, 22, 443.

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