• Artemisinin

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SKU: A098

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Description
Artemisinin is a sesquiterpene lactone compound with anti-malarial activity against cerebral malaria causing and drug-resistant strains of Plasmodium falciparum. Artemisinin and some of its derivatives have anti-tumor properties and are effective against other clinically significant parasites.

 

    CAS Number

    63968-64-9

    Molecular Formula

    C15H22O5

    Molecular Weight

    282.33

    Mechanism of Action

    The mechanism of action of artemisinin has not been proven and is not fully understood. A recent study identified 124 artemisinin binding sites in Plasmodium falciparum suggesting multiple mechanisms of action.

    Storage Conditions

    ≤30°C

References

    References

    Walters, Michael. "Faculty of 1000 Evaluation for Haem-activated Promiscuous Targeting of Artemisinin in Plasmodium Falciparum." F1000 - Post-publication Peer Review of the Biomedical Literature 6 (2015)

    Klayman, D. "Qinghaosu (artemisinin): An Antimalarial Drug from China."Science 228.4703 (1985): 1049-055.

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