• Antimycin A1, EvoPure� packaged and labeled in glass vial.

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SKU: A127

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Description
Antimycin A1 is the most hydrophobic of the four analogues of the antimycin A complex. Although broadly active as respiration inhibitors, more recent investigation has highlighted the importance of individual members of the complex as bioprobes.

Antimycin A1 is soluble in ethanol, methanol, DMF and DMSO.

    CAS Number

    642-15-9

    Molecular Formula

    C28H40N2O9

    Molecular Weight

    548.6

    Mechanism of Action

    Antimycin A1 inhibits angiogenesis via a decrease in VEGF production caused by inhibition of HIF-1a activation.

    Storage Conditions

    -20°C

Specifications

    Appearance

    White solid

References

    References

    Antimycin A1, an antibiotic with insecticidal and miticidal properties. Kido G.S. & Spyhalski E. Science 1950, 112, 172.

    Inhibition of angiogenesis and HIF-1a activity by antimycin A1. Maeda M. et al. Biol. Pharm. Bull. 2006, 29, 1344.

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