• Ansatrienin B, EvoPure� packaged and labeled in glass vial.

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SKU: A126

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Description
Ansatrienin B, also known as Mycotrienin II and Antibiotic T 23II, was isolated from a Streptomyces sp.. Closely related to the cytotrienins and trienomycins, it displays potent activity against tumor cell lines and inhibits osteoclastic bone resorption. Ansatrienin B also significantly potentiates the action of several clinical anti-cancer agents.

Ansatrienin B is soluble in ethanol, methanol, DMF and DMSO. 

    CAS Number

    82189-04-6

    Molecular Formula

    C36H50N2O8

    Molecular Weight

    638.8

    Storage Conditions

    -20°C

Specifications

    Appearance

    Pale yellow powder

References

    References

    Mycotrienins. A new class of potent inhibitors of osteoclastic bone resorption. Feuerbach D. et al. , J. Biol. Chem. 1995, 270, 25949. 

    Potentiation of mitomycin C, 6-mercaptopurine, bleomycin, cis-diamminedichloroplatinum and 5-fluoro-uracil by mycotrienins and mycotrienols. Kuwano M. et al. , Gann. 1983, 74, 759. 

    Studies on mycotrienin antibiotics, a novel class of ansamycins. II. Structure elucidation and biosynthesis of mycotrienins I and II. Sugita M. et al. , J. Antibiot. 1982, 35, 1467.

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