• Amodiaquine HCl packaged and labeled.

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SKU: A085

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Description

Amodiaquine HCl is an antimalarial 4-aminoquinoline compound with a similar structure and mechanism of action to chloroquine.

    CAS Number

    6398-98-7

    Molecular Formula

    C20H22ClN3O •2HCl •2H2O

    Molecular Weight

    464.81

    Mechanism of Action

    The mechanism of action for amodiaquine is not entirely clear; however, it is thought to inhibit digestion of hemoglobin in malarial parasites.

    Storage Conditions

    -20°C

    Tariff Code

    2933.49.2600

    Spectrum

    Amodiaquine has a similar spectrum of activity as chloroquine (Plasmodium vivax, Plasmodium malariae) however; it has shown to be more effective against chloroquine resistant Plasmodium falciparum.

Specifications

    Form

    Powder

    Appearance

    Yellow Crystalline Powder

    Source

    Synthetic

    Water Content (Karl Fisher)

    7.0-9.0%

    Assay

    (On Dried Basis): 97.0-103.0%

    Residue On Ignition

    ≤0.2%

    Impurities

    Individual Impurity: ≤0.5%
    Total Impurities: ≤1.0%

References

    References

    Sangkuhl, Katrin. "Amodiaquine Pathway, Pharmacokinetics." PharmGKB. N.p., n.d. Web. 2 Oct. 2013.

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