• Adenine 9-ß-D-arabinofuranoside (Vidarabine)

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SKU: A091

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Description
Adenine 9-ß-D-arabinofuranoside (Vidarabine) is a purine nucleoside with anti-viral activity against some DNA viruses including herpesviruses and varicella zoster viruses.

    CAS Number

    5536-17-4

    Molecular Formula

    C10H13N5O4

    Molecular Weight

    267.24

    Mechanism of Action

    Adenine 9-ß-D-arabinofuranoside (Vidarabine) inhibits DNA synthesis in DNA viruses by becoming incorporated into viral DNA and ultimately producing a faulty DNA sequence.

    Storage Conditions

    -20°C

    Spectrum

    Adenine 9-ß-D-arabinofuranoside is active against poxviruses, herpesviruses, rhabdoviruses, and hepadnaviruses.

Specifications

    Form

    Powder

    Appearance

    White crystalline powder

    pH

    6.0 - 7.0

    Optical Rotation

    -56.0° - -65.0°

    Assay

    (HPLC) 98.0 - 102.0%

References

    References

    Pollard, R. B. "Effect of Vidarabine on Chronic Hepatitis B Virus Infection." JAMA: The Journal of the American Medical Association 239.16 (1978): 1648-650.

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