SKU: A113

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Description
Actagardin is a high molecular weight tetracyclic antibiotic produced by several species of Actinoplanes. Actagardin is an antibiotic in which the macrocyclic rings are formed by thioether, rather than disulphide, bridges. Actagardin is a potent Gram positive and Gram negative antibiotic. Actagardin acts by inhibition of peptidoglycan biosynthesis.

Actagardin is soluble in ethanol, methanol, DMF and DMSO.

    CAS Number

    59165-34-3

    Molecular Formula

    C81H124N20O24S4

    Molecular Weight

    1890.2

    Mechanism of Action

    Actagardin acts by inhibition of peptidoglycan biosynthesis.

    Storage Conditions

    -20°C

Specifications

    Appearance

    White to off white solid

References

    References

    Gardimycin, a new antibiotic from Actinoplanes. I. Description of the producer strain and fermentation studies. Parenti F. et al. J. Antibiot. 1976, 29, 501. 

    Gardimycin, a new antibiotic from Actinoplanes. II Isolation and preliminary characterisation. Coronelli C. et al. J. Antibiot. 1976, 29, 507.

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