• Acalabrutinib

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SKU: A144

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Description
Acalabrutinib is a highly selective, irreversible inhibitor of Bruton's tyrosine kinase (BTK), and is being considered for use in the treatment of relapsed chronic lymphoid leukemia. Mutations in BTK result in a variety of B-cell related malignancies, as it upsets the B cell's signalling pathways.

    CAS Number

    1420477-60-6

    Molecular Formula

    C26H23N7O2

    Molecular Weight

    465.52

    Storage Conditions

    -20°C

References

    References

    Wu, J., Zhang, M., & Liu, D. (2016). Acalabrutinib (ACP-196): A selective second-generation BTK inhibitor. Journal of Hematology & Oncology, 9(1). doi:10.1186/s13045-016-0250-9

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