Thiamine hydrochloride packaged and labeled.

T02525 g
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T025100 g
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  • Description

    Thiamine is a member of the B vitamins (B1) and is commonly used in cell culture media. Thiamine is freely soluble in water (500 mg/mL) and glycerol, and slightly soluble in ethanol (10 mg/mL).

    Mechanism of Action

    Thiamine is involved in the synthesis of neurotransmitters acetylcholine and gamma-aminobutyric acid (GABA) in mammalian cells. In addition, thiamine serves as a precursor for thiamine pyrophosphate (TPP), a coenzyme involved in amino acid and carbohydrate synthesis.

    • Eukaryotic Cell Culture Applications

      Because of its active role in normal cell processes, thiamine HCl is commonly used as a cell culture supplement.

    • References

      Butterworth, R. F. "Neurotransmitter Function in Thiamine-deficiency Encephalopathy." Neurochemistry International 4.6 (1982): 449-64. Web. 31 Aug. 2012.



    Tariff Code


    Related Documents

    For in vitro research use only. Not suitable for human or animal consumption. For MSDSs not available online, please email a request to

  • CAS Number67-03-8
    Molecular FormulaC12H17ClN4OS · HCl
    Molecular Weight337.27
    AppearanceWhite Crystalline Powder
    SolubilityEthanol: 10 mg/mL
    Ethanol (95%): 3 mg/mL
    Glycerol: Freely soluble
    Water: Freely Soluble
    Water Content (Karl Fisher)≤5.0%
    Absorbance400nm: ≤0.025
    Melting Point248 °C (dec.)
    Storage Conditions2-8 °C
    Assay98.0 - 102.0%