Vancomycin HCl, USP packaged and labeled.

V001250 mg
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V0011 g
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  • Description

    Vancomycin HCl, USP is a bactericidal glycopeptide antibiotic and has been used to treat infections caused by multi drug resistant bacteria including methicillin resistant Staphylococcus aureus (MRSA).

    Vancomycin HCl, USP is freely soluble in water. Click here for more vancomycin products.


    Vancomycin prevents peptidoglycan synthesis by two separate mechanisms. One mechanism prevents N-acetylmuramic acid (NAM) and N-acetylglucosamine (NAG) from linking together forming the peptidoglycan backbone. The second mechanism prevents crosslinking between amino acid residues in the peptidoglycan chain.


    Vancomycin inhibits growth of many Gram positive bacteria including the antibiotic resistant superbug, MRSA (Methicillin resistant Staphylococcus aureus). Vancomcyin is effective for treating MRSA infections because it inhibits cell wall synthesis through a different mechanism than β-lactam antibiotics.



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    For in vitro research use only. Not suitable for human or animal consumption. For MSDSs not available online, please email a request to

  • CAS Number1404-93-9
    Molecular FormulaC66H75Cl2N9O24 · HCl
    Molecular Weight1485.71
    AppearanceWhite or light brown powder
    Purity Level>80%
    Impurity ProfileVancomycin Didechloro Impurity; Didechloro Vancomycin B|||C66H77N9O24|1379.51| Impurity A| Vancomycin N-Desmethyl||C65H73Cl2N9O24|1433.41455| Impurity B| Vancomycin B; Vancomycin B Diacid ||C65H74Cl2N8O25|1448.41422| Impurity C| Agluco Vancomycin B; Vancomycin B Aglycone; Aglucovancomycin B||C53H52Cl2N8O17|1142.28275| Impurity D| Desvancosaminyl Vancomycin B||C59H62Cl2N8O22|1304.33557|
    SolubilityAcetone: Insoluble
    Methanol: Moderately soluble
    Higher Alcohols: Insoluble
    Ether: Insoluble
    Water: Freely soluble
    SourceStreptomyces Orientalis
    Storage Conditions2-8 °C, protect from light
  • Protocols


    Courvalin, Patrice. "Vancomycin Resistance in Gram-Positive Cocci." Oxford Journals(2006): 25-34. Clinical Infectious Diseaes. Web. 21 Aug. 2012.

    Pollock, H.M., Holt J., and Murray C., Comparison of susceptibilities of anaerobic bacteria to cefemenoxime, ceftriaxone and other antimicrobial compounds, Antimicrob. Agents Chemother., Vol. 23, pp.780-783, 1983

    Silva J.A. and Fukai S., The impact of carbenicillin, cefotaxime and vancomycin on chrysanthemum and tobacco TCL morphogenesis and Agrobacterium growth, J. Appl. Hort., Vol. 3(1), pp. 3-12, 2001.

    Joshi, S., Ray, P., Manchanda, V., Bajaj, J., Chitnis, D. S., Gautam, V., &...Balaji, V. (2013). Methicillin resistant Staphylococcus aureus (MRSA) in India: Prevalence & susceptibility pattern. Indian Journal Of Medical Research, 137(2), 363-369