G418 Geneticin, Transfection, Antibiotic, High Purity G418, Powder

Products: EvoPure^®; Antimicrobials; • for microbiology; • for plant biology; • for cell biology; Electrophoresis Reagents

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Antimicrobials > Anti-fungals/Anti-bacterials/Gene Selectors > Aminoglycosides > G418 Disulfate

G418 Disulfate, Powder

Item No.G001-1g
Size1g
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Price ($)79.5439.00

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Other Packages

5g/US$ 137.00

25g/US$ 548.00

4 x 25g/US$ 1600.00

Spotlight Products

G418 (also known as Geneticin) is an aminoglycoside antibiotic that is produced by Micromonospora rhodorangea. It is main used as gene transfer and selection reagent in molecular biology. Resistant to G418 is conferred by the neo gene from Tn5 encoding an aminoglycoside 3‘-phosphotransferase, APH 3‘ II. As a primary manufacturer of G418, TOKU-E produces various G418 purities, the highest being G418-EvoPure^®. TOKU-E's high purity EvoPure^® line of antibiotics is virtually free from any and all impurities.

MSDS PDS

Specifications

Application field:molecular biology
Mechanism:G418 blocks polypeptide synthesis in eukaryotic cells by binding irreversibly to 80S ribosomes and therefore disrupting their proofreading capability.
Molecular Weight:692.71
CAS NO.:108321-42-2
Purity:Assay on dry basis: >760μg/mg; Assay (as is): >700μg/mg
Molecular Formula: C₂₀H₄₀N₄O₁₀· 2H₂SO₄
Composition: Ammonia: <0.1%, ED₅₀ Resistant: ≥2500µg/ml; ED₅₀ Sensitive: ≤400µg/ml, Elemental Analysis: C:28.8-36.07%, H:5.76-7.76%, N: 6.72-8.41%, Waters of Hydration: 0-6
Solubility: 100mg/ml in H₂O: Clear and colorless or light yellow solution
Water content: Karl Fischer: <12.0%
Optical rotation: +104º to +121º