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Novel compound holds promise for MRSA(Post)
Antibiotic resistance (AMR) poses a threat to global health and Staphylococcus aureus has become one of the most notable multidrug-resistant pathogens, causing nearly 1 million deaths globally. S.
Artificial Intelligence uncovers 'sleeper' microbes(Post)The World Health Organization has declared that antimicrobial resistance (AMR) is one of the top global public health threats. One well documented possibility for why an infection would return aft ...
A Genomic, Transcriptomic and Proteomic Look at the GE2270 Producer Planobispora rosea(Page)GE2270 was first isolated from P. rosea in 1991, and P. rosea is still used on an industrial scale to produce GE2270. Antibiotic GE2270 is active against g ...
Dithiazole thione derivative as competitive NorA efflux pump inhibitor(Page)When combating a multi-drug resistant pathogen, sometimes it is better to target the mechanism of the resistance rather than to develop new antibiotics. Efflux pumps remove the antibiotic from the ce ...
Bacillusin A, an Antibacterial Macrodiolide from Bacillus amyloliquefaciens AP183(Page)Ravu et all extracted a new macrocyclic polyene antibiotic, bacillusin A from Bacillus amyloliquefaciens strain (AP183) and found that it shows potent antibacterial activity against methicillin-resis ...
Auranofin exerts broad-spectrum bactericidal activities by targeting thiol-redox homeostasis(Page)Drug repurposing is a time efficient way to discover new antimicrobial drugs, reducing approval time and cost. Auranofin is an FDA approved drug for rheumatoid arthritis ...
The Oxazolidinone Class of Antibiotics(Page)About OxazolidinonesOverviewThe oxazolidinone class of antibiotics is a relatively recent addition to the antimicrobial world and have been found to be especially useful in treating infections caused ...
In the Literature(Page)In the literature TOKU-E Company products are widely distributed to major life science companies and research labs around the world. Over the past several years, scientists in various disc ...
Antibiotic Classification Table(Page)Antibiotic Classification and General Information Protein synthesis inhibitors Major groups: aminoglycosides, tetracyclines, macrolides General mechanism of action: Protein synthesis i ...
Overcoming Multi-Drug Resistant Microbes(Page)Common and Emerging Drug-Resistant Pathogens Some of the most notable multi-drug resistant bacteria include Mycobacterium tuberculosis (TB), Methicillin-resistant Staphylococ ...