Amikacin Sulfate, USP (1:1.8) is the sulfate salt of Amikacin and contains an Amikacin:Sulfate ratio of 1:1.8. Amikacin is a semi-synthetic, broad-spectrum aminoglycoside antibiotic derived from its counterpart, Kanamycin A. It was patented in 1971 and came into commercial use in 1976. The presence of the amino-hydroxy-butyryl group prevents enzymatic modification of Amikacin at multiple positions. This renders Amikacin a more effective decontaminating agent, as microorganisms which develop resistance to other aminoglycosides remain susceptible to Amikacin. This also gives Amikacin a broader spectrum than the other aminoglycosides currently in use. Amikacin is commonly used for veterinary research, antimicrobial susceptibility testing and studying bacterial translation.
Amikacin Sulfate, USP (1:1.8) is soluble in water.
This product conforms to United States Pharmacopoeia specifications.
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